{"id":18095,"date":"2022-10-23T07:10:57","date_gmt":"2022-10-23T07:10:57","guid":{"rendered":"http:\/\/www.pidsphil.org\/home\/?page_id=18095"},"modified":"2022-12-04T10:29:37","modified_gmt":"2022-12-04T10:29:37","slug":"journal-2022-vol-23-no-2-case-series","status":"publish","type":"page","link":"https:\/\/www.pidsphil.org\/home\/journal-2022-vol-23-no-2-case-series\/","title":{"rendered":"Journal 2022 Vol.23 No.2 Case Series"},"content":{"rendered":"<p><strong>Cancer and Chemotherapy in Pediatric COVID-19: A Case Series<\/strong><br \/>\n<em><strong>Meg Tuazon, M.D., Mary Crist Delos Santos-Jamora, M.D., Sabrina Florendo-Villanueva ,M.D. and Rainelda Panlilio-Runez, M.D.<\/strong><\/em><br \/>\n<strong>ABSTRACT<br \/>\nObjectives:<\/strong> This case series aims to present three cases of pediatric cancer \u2013 two acute leukemia and one solid tumor with active COVID-19 infection who underwent chemotherapy<br \/>\n<strong>Methodology:<\/strong> Three cases of pediatric cancer who tested positive for SARS-CoV2 are presented. All proceeded with scheduled chemotherapy despite active COVID-19 infection. Two had no post-chemotherapy complications, while one had febrile neutropenia and hospital-acquired pneumonia.<br \/>\n<strong>Results:<\/strong> In this case series, COVID-19 infection in pediatric patients with cancer does not appear to be more severe compared with the general population. The severity of signs and symptoms can be attributed to a lower Cycle Threshold (CT) value and a co-infection. COVID-19 infection did not change the course and post-chemotherapy complications in all cases.<br \/>\n<strong>Conclusion:<\/strong> Patient demographics, comorbidities and type of malignancy played an essential role in the pre- and post-chemotherapy outcome. Individual patient factors including CT values, comorbidities, co-infections, COVID19 disease severity classification, and blood count picture are also instrumental in the management and outcome of these cases. Pediatric cancer treatment should be a priority during active COVID-19 infection.<br \/>\n<strong>Keywords:<\/strong> COVID-19, Chemotherapy, Cancer, Children<br \/>\n<a href=\"https:\/\/doi.org\/10.56964\/pidspj20222302004\"><strong>https:\/\/doi.org\/10.56964\/pidspj20222302004<\/strong><\/a><br \/>\n<a href=\"https:\/\/www.pidsphil.org\/home\/wp-content\/uploads\/2022\/10\/005_PIDSP-vol-23-no-2_TUAZON_3CS-layout-rev-1.pdf\"><strong>| View Full Article in PDF format |<\/strong><\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Cancer and Chemotherapy in Pediatric COVID-19: A Case Series Meg Tuazon, M.D., Mary Crist Delos Santos-Jamora, M.D., Sabrina Florendo-Villanueva ,M.D. and Rainelda Panlilio-Runez, M.D. ABSTRACT Objectives: This case series aims to present three cases of pediatric cancer \u2013 two acute leukemia and one solid tumor with active COVID-19 infection who underwent chemotherapy Methodology: Three cases  [&#8230;]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-18095","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/www.pidsphil.org\/home\/wp-json\/wp\/v2\/pages\/18095","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.pidsphil.org\/home\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.pidsphil.org\/home\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.pidsphil.org\/home\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.pidsphil.org\/home\/wp-json\/wp\/v2\/comments?post=18095"}],"version-history":[{"count":6,"href":"https:\/\/www.pidsphil.org\/home\/wp-json\/wp\/v2\/pages\/18095\/revisions"}],"predecessor-version":[{"id":18476,"href":"https:\/\/www.pidsphil.org\/home\/wp-json\/wp\/v2\/pages\/18095\/revisions\/18476"}],"wp:attachment":[{"href":"https:\/\/www.pidsphil.org\/home\/wp-json\/wp\/v2\/media?parent=18095"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}