{"id":17513,"date":"2022-08-29T05:03:01","date_gmt":"2022-08-29T05:03:01","guid":{"rendered":"http:\/\/www.pidsphil.org\/home\/?page_id=17513"},"modified":"2025-06-14T05:09:44","modified_gmt":"2025-06-14T05:09:44","slug":"journal-2017-vol-18-no-2-original-articles-2","status":"publish","type":"page","link":"https:\/\/www.pidsphil.org\/home\/journal-2017-vol-18-no-2-original-articles-2\/","title":{"rendered":"Journal 2017 Vol.18 No.2 Original Articles 2"},"content":{"rendered":"<div class=\"volume\"><strong><span class=\"journalTitle\"><span style=\"color: #800000;\">Journal 2017 Vol.18 No.2<\/span><\/span><\/strong><\/div>\n<div class=\"volume\"><strong><span class=\"journalTitle\">A Meta-Analysis on GeneXpert Using Stool Samples in Diagnosing Pediatric Pulmonary Tuberculosis <\/span><\/strong><br \/>\n<em><strong>Othella Mary Ann S. Cacayorin, M.D.<\/strong><\/em><\/div>\n<div class=\"volume\"><strong>Abstract<\/strong><\/div>\n<div class=\"volume\"><strong> Objectives: <\/strong> To find an alternative specimen for GeneXpert assay in the diagnosis of pediatric pulmonary tuberculosis (PTB). To determine the sensitivity and specificity of using stool samples as an alternative to sputum for GeneXpert assay.<\/div>\n<div class=\"volume\"><strong> Methods:<\/strong> A systematic search was done using an electronic database (e.g. Pubmed). Using the keywords \u201cGeneXpert\u201d, \u201ctuberculosis\u201d, \u201cStool samples\u201d. QUADAS-2 checklist was used in assessing the studies gathered. Revman 5.3 was used to determine the sensitivity and specificity of the study included in this meta-analysis.<\/div>\n<div class=\"volume\"><strong> Results: <\/strong>A total of 185 stool samples were included in this review, which showed a median sensitivity of 77% (IQR 0.63-0.87) and median specificity of 98% (IQR 0.95-1.0).<\/div>\n<div class=\"volume\"><strong> Conclusion:<\/strong> Despite the heterogeneous sensitivity, GeneXpert has a high specificity, which enabled rapid diagnosis of pulmonary tuberculosis promoting timely initiation of appropriate therapy.<\/div>\n<div><strong><a href=\"https:\/\/doi.org\/10.56964\/pidspj20171802003\">https:\/\/doi.org\/10.56964\/pidspj20171802003<\/a><\/strong><\/div>\n<p><strong><a href=\"https:\/\/www.pidsphil.org\/home\/wp-content\/uploads\/2018\/12\/jo53_ja03.pdf\" target=\"_new\" rel=\"noopener\">View Full Article in PDF format<\/a><\/strong><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Journal 2017 Vol.18 No.2 A Meta-Analysis on GeneXpert Using Stool Samples in Diagnosing Pediatric Pulmonary Tuberculosis Othella Mary Ann S. Cacayorin, M.D. Abstract Objectives: To find an alternative specimen for GeneXpert assay in the diagnosis of pediatric pulmonary tuberculosis (PTB). To determine the sensitivity and specificity of using stool samples as an alternative to sputum  [&#8230;]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-17513","page","type-page","status-publish","hentry"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.8 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Journal 2017 Vol.18 No.2 Original Articles 2 - Pediatric Infectious Disease Society of the Philippines<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.pidsphil.org\/home\/journal-2017-vol-18-no-2-original-articles-2\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Journal 2017 Vol.18 No.2 Original Articles 2 - Pediatric Infectious Disease Society of the Philippines\" \/>\n<meta property=\"og:description\" content=\"Journal 2017 Vol.18 No.2 A Meta-Analysis on GeneXpert Using Stool Samples in Diagnosing Pediatric Pulmonary Tuberculosis Othella Mary Ann S. Cacayorin, M.D. Abstract Objectives: To find an alternative specimen for GeneXpert assay in the diagnosis of pediatric pulmonary tuberculosis (PTB). To determine the sensitivity and specificity of using stool samples as an alternative to sputum [...]\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.pidsphil.org\/home\/journal-2017-vol-18-no-2-original-articles-2\/\" \/>\n<meta property=\"og:site_name\" content=\"Pediatric Infectious Disease Society of the Philippines\" \/>\n<meta property=\"article:modified_time\" content=\"2025-06-14T05:09:44+00:00\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data1\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/www.pidsphil.org\\\/home\\\/journal-2017-vol-18-no-2-original-articles-2\\\/\",\"url\":\"https:\\\/\\\/www.pidsphil.org\\\/home\\\/journal-2017-vol-18-no-2-original-articles-2\\\/\",\"name\":\"Journal 2017 Vol.18 No.2 Original Articles 2 - Pediatric Infectious Disease Society of the Philippines\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/www.pidsphil.org\\\/home\\\/#website\"},\"datePublished\":\"2022-08-29T05:03:01+00:00\",\"dateModified\":\"2025-06-14T05:09:44+00:00\",\"breadcrumb\":{\"@id\":\"https:\\\/\\\/www.pidsphil.org\\\/home\\\/journal-2017-vol-18-no-2-original-articles-2\\\/#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\\\/\\\/www.pidsphil.org\\\/home\\\/journal-2017-vol-18-no-2-original-articles-2\\\/\"]}]},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\\\/\\\/www.pidsphil.org\\\/home\\\/journal-2017-vol-18-no-2-original-articles-2\\\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\\\/\\\/www.pidsphil.org\\\/home\\\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Journal 2017 Vol.18 No.2 Original Articles 2\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\\\/\\\/www.pidsphil.org\\\/home\\\/#website\",\"url\":\"https:\\\/\\\/www.pidsphil.org\\\/home\\\/\",\"name\":\"Pediatric Infectious Disease Society of the Philippines\",\"description\":\"Pediatric Infectious Disease Society of the Philippines\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\\\/\\\/www.pidsphil.org\\\/home\\\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-US\"}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Journal 2017 Vol.18 No.2 Original Articles 2 - Pediatric Infectious Disease Society of the Philippines","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/www.pidsphil.org\/home\/journal-2017-vol-18-no-2-original-articles-2\/","og_locale":"en_US","og_type":"article","og_title":"Journal 2017 Vol.18 No.2 Original Articles 2 - Pediatric Infectious Disease Society of the Philippines","og_description":"Journal 2017 Vol.18 No.2 A Meta-Analysis on GeneXpert Using Stool Samples in Diagnosing Pediatric Pulmonary Tuberculosis Othella Mary Ann S. Cacayorin, M.D. Abstract Objectives: To find an alternative specimen for GeneXpert assay in the diagnosis of pediatric pulmonary tuberculosis (PTB). 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