{"id":17343,"date":"2022-08-25T10:47:03","date_gmt":"2022-08-25T10:47:03","guid":{"rendered":"http:\/\/www.pidsphil.org\/home\/?page_id=17343"},"modified":"2025-06-14T04:22:46","modified_gmt":"2025-06-14T04:22:46","slug":"journal-2021-vol-22-no-1-original-articles-3","status":"publish","type":"page","link":"https:\/\/www.pidsphil.org\/home\/journal-2021-vol-22-no-1-original-articles-3\/","title":{"rendered":"Journal 2021 Vol.22 No.1 Original Articles 3"},"content":{"rendered":"<p><strong><span style=\"color: #800000;\">Journal 2021 Vol.22 No.1<\/span><\/strong><br \/>\n<strong>Outcomes of HIV-Exposed Infants enrolled in the Prevention of Mother to Child Transmission of HIV (PMTCT) Program in Philippine General Hospital: An 8-year Retrospective Study<\/strong><br \/>\n<em><strong>Anna Soleil Cheshia V. Tan, M.D. DPPS<\/strong><\/em><br \/>\n<strong>Abstract<br \/>\nBackground:<\/strong> Our country has the fastest growing number of HIV cases in the Asia-Pacific region with a 203% increase from 2010 to 2018. MTCT represents 6% of infections in children and interventions such as the PMTCT program are essential to help reduce new infant infections.<br \/>\n<strong>Objective:<\/strong> To determine the outcomes of HIV-exposed infants born in PGH from 2010 to 2018 enrolled in the PMTCT program. To analyze the association of maternal and neonatal clinicodemographic factors to MTCT of HIV.<br \/>\n<strong>Methods:<\/strong> A retrospective cohort study using data collected from medical records of HIV exposed infants enrolled in the program.<br \/>\n<strong>Results:<\/strong> Out of 117 mother-infant pairs, only 70 met the eligibility criteria. Maternal factors showed that majority have: timely antenatal visit (56\/70), maternal HIV diagnosis (70\/70) and ART initiation (67\/70) prior to delivery, triple lifelong maternal ART (69\/70), CD4 &gt;200 prior to delivery (52\/70) and cesarean delivery (67\/70). Amongst the infant factors-early infant prophylaxis (60\/62), &gt;4weeks prophylaxis duration (62\/70) and replacement feeding (62\/70) were noted in the majority. 2\/70 infants were HIV positive. Mortality rate was 1.4% and 50% for HIV infected infants. Overall LTFU rate was 33.3%. Logistic regression showed that maternal co-infection with Hepatitis B(p=0.0275) was a possible determinant of MTCT. Infant HIV prophylaxis duration of &gt;4 weeks had higher survival proportion(p=.0001).<br \/>\n<strong>Conclusion:<\/strong> The HIV MTCT rate was 2.86% upon implementation of our PMTCT program, meeting the &lt;5% goal of WHO, suggesting that the program was an effective health intervention strategy. The high LTFU rate though should be considered in the evaluation of the program effectiveness.<br \/>\n<strong>Keywords:<\/strong> PMTCT, HIV-Exposed Infant, ARV prophylaxis, HIV Philippines<br \/>\n<strong><a href=\"https:\/\/doi.org\/10.56964\/pidspj2021220107\">https:\/\/doi.org\/10.56964\/pidspj2021220107<\/a><\/strong><br \/>\n<strong><a href=\"https:\/\/www.pidsphil.org\/home\/wp-content\/uploads\/2021\/05\/07-Vol-22-No-1_Tan_Outcomes-of-HIV-Exposed-Infants-_FORMATTED_v6.pdf\" target=\"_\" rel=\"noopener\">View Full Article in PDF format<\/a><\/strong><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Journal 2021 Vol.22 No.1 Outcomes of HIV-Exposed Infants enrolled in the Prevention of Mother to Child Transmission of HIV (PMTCT) Program in Philippine General Hospital: An 8-year Retrospective Study Anna Soleil Cheshia V. Tan, M.D. DPPS Abstract Background: Our country has the fastest growing number of HIV cases in the Asia-Pacific region with a 203%  [&#8230;]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-17343","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/www.pidsphil.org\/home\/wp-json\/wp\/v2\/pages\/17343","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.pidsphil.org\/home\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.pidsphil.org\/home\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.pidsphil.org\/home\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.pidsphil.org\/home\/wp-json\/wp\/v2\/comments?post=17343"}],"version-history":[{"count":6,"href":"https:\/\/www.pidsphil.org\/home\/wp-json\/wp\/v2\/pages\/17343\/revisions"}],"predecessor-version":[{"id":19988,"href":"https:\/\/www.pidsphil.org\/home\/wp-json\/wp\/v2\/pages\/17343\/revisions\/19988"}],"wp:attachment":[{"href":"https:\/\/www.pidsphil.org\/home\/wp-json\/wp\/v2\/media?parent=17343"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}